Demethylation of a steroid methyl ether with concomitant ring expansion
IA Blair, RG Frith, G Phillipou and CJ Seaborn
Australian Journal of Chemistry
31(10) 2333 - 2335
Published: 1978
Abstract
Demethylation of pregn-5-ene-3β,20β-diol dimethyl ether with ferric chloride/acetic anhydride is shown to form the ring-expanded steroid 17α-methyl-D-homoandrost-5-ene-3β,17aβ-diol (1) in 75% isolated yield.
https://doi.org/10.1071/CH9782333
© CSIRO 1978
