Kinetic studies of the reactions of glutathione with aromatic compounds

Abstract

Kinetic results for the non-enzyme-catalysed reaction of glutathione and 1-chloro-2,4-dinitrobenzene are reported. Positive kinetic salt effects are observed in the presence of sodium chloride. The effect is more pronounced at higher temperature. Glutathione also reacts with 1,3,5-trinitrobenzene to form a Meisenheimer complex.