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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

The Hydrolysis of Amides in Acid Solutions – A New Kinetic Equation

CJ Giffney and CJ O'Connor

Australian Journal of Chemistry 29(2) 307 - 314
Published: 1976

Abstract

A new kinetic equation, based on a reaction mechanism in which water attacks the N-protonated conjugate acid in the rate-determining step, is formulated for the acid-catalysed hydrolysis of arnides. The equation is well fitted by 60 sets of data for hydrolysis of both aliphatic and aromatic amides.

https://doi.org/10.1071/CH9760307

© CSIRO 1976

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