Molecular asymmetry in sugar derivatives

Abstract

The N.M.R. spectra of a series of derivatives of the four trihydroxyglutaric acids (1)-(4) have shown non-equivalence of the hydrogen atoms attached to C 2 and C 4 in the D- and L-arabino series (3) and(4) which is not observed in the derivatives of symmetrical D- ribo and D-xylo acids (1) and (2). Vicinal coupling constants have led to predictions regarding the major conformations.