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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Organophosphorus compounds. XV. Synthesis of 2-Ethoxy-1-methyl-1,2-azaphospholidine 2-oxide

DJ Collins, JW Hetherington and JM Swan

Australian Journal of Chemistry 27(8) 1759 - 1765
Published: 1974

Abstract

The reaction of diethyl 3-bromopropylphosphonate with phosphorus pentachloride in carbon tetrachloride gave ethyl 3-bromopropylphosphonochloridate, which upon reaction with anhydrous methylamine at -15º gave ethyl N-methyl-P-3-bromopropylphosphonamidate. Treatment of this phosphonamidate with sodium hydride in boiling xylene gave 2-ethoxy-1-methyl-l,2-azaphospholidine 2-oxide. Some other possible routes to this compound were investigated.

https://doi.org/10.1071/CH9741759

© CSIRO 1974

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