The oxidation of benzoylthiourea
RLN Harris and LT Oswald
Australian Journal of Chemistry
27(7) 1531 - 1535
Published: 1974
Abstract
Oxidation of benzoylthiourea with bromine gives initially N1,N3-dibenzoyl-α,α-dithiobisformamidine dihydrobromide (5) which, on recrystallization or treatment with polar solvents, rearranges and cyclizes with elimination of ammonium bromide or sulphur to give derivatives of 3H-1,2,4-dithiazole and 1,2,4-thiadiazole respectively. The former reaction is unprecedented in thiourea oxidations and occurs exclusively under suitably chosen conditions.https://doi.org/10.1071/CH9741531
© CSIRO 1974