Alkaloids of Nemuaron vieillardii (Monimiaceae)

Abstract

Bark of the New Caledonian monimiaceous plant Nemuaron vieillardii contains the alkaloids laurotetanine, N-methyllaurotetanine, norisocorydine, atheroline, O-methylflavinantine, and a new bisbenzylisoquinoline alkaloid nemuarine, which is the major alkaloid of the leaves. Nemuarine is shown to have a novel structure with a 5-6? ether link between the isoquinoline residues.