The self-association of Pyrrolid-2-one in acetonitrile and chloroform: An N.M.R. spectroscopic study

Abstract

The self-association of pyrrolid-2-one has been studied in CDCl₃ and CD₃CN at several temperatures by the use of high resolution nuclear magnetic resonance spectroscopy. The enthalpies of self-association of the lactam in the two solvents have been measured and are in reasonable agreement with those for similar systems determined by the use of other methods. The enthalpy of salvation of pyrrolid-2-one in CHCl₃ has also been measured. A discussion on the validity of the approximations used in the calculations of the thermodynamic parameters has been included.