The preparation and some reactions of symmetrical Dichloro-1,3,5-triazine derivatives of polyethylene glycols

Abstract

The preparation is described of the bis(dichlorotriazinyl) derivatives of diethylene and triethylene glycol and of the bis(chlorobutylaminotriazinyl), bis(chlorobutylthiotriazinyl), and bis(chlorophenoxytriazinyl) derivatives of diethylene glycol. In addition, there is described the preparation of a water-soluble bis(dichlorotriazinyl) derivative of a polyethylene glycol and evidence is produced for its reactions with glycine, γ-aminobutyric acid, N- acetylcysteine, glutathione, and tyrosine.