New imidazole alkaloids from a Glochidion species (family Euphorbiaceae)

Abstract

The leaves of a Glochidion species, probably Glochidion philippicum (Cav.) C. B. Rob., of the family Euphorbiaceae, contain three new interrelated imidazole alkaloids, glochidine (I), glochidicine (II), and N^α-4?-oxodecanoylhistamine (III), together with the known alkaloid N^α-cinnamoylhistamine. The bark of this species contains only glochidicine and N^α-cinnamoylhistamine.