A Study of the Thorpe-Ingold Effect: The Reaction of Potassium Hydroxide with a Lactone of Ethyl α-Bromo-α'-hydroxy-1,1-cyclohexane Diacetate

Abstract

Treatment of a lactone of ethyl α-bromo-α?-hydroxy-1,1-cyclohexane diacetate with aqueous potassium hydroxide formed αα'-dihydroxyl-1,1-cyclohexanediacetic acid. The cyclohexanespirocyclopropanol-2,3-dicarboxylic acid (I), an important member of a series of compounds illustrating ring-chain tautomerism, was not observed.