Methylsteroids. V. The faciliation of hydrolysis of sterically hindered acetoxy groups by carbonyl groups in the Lanosterol series
CS Barnes
Australian Journal of Chemistry
11(4) 546 - 561
Published: 1958
Abstract
The facilitation of basic hydrolysis of sterioally hindered acetoxy groups has been ex mined among the lanosterol oxo derivatives. It is found that an llp-acetoxyl may be hydrolysed under mild conditions in the presence of a 7-oxo group or more easily when a 3,7-dioxo grouping is present. The 7α-acetoxy group is resistant to basic hydrolysis except in the presence of a 3- or 11-oxo group. Possible reasons for these effects are discussed.
https://doi.org/10.1071/CH9580546
© CSIRO 1958