Amino Acids and Peptides. IV. Intermediates for the synthesis of certain cystine-containing peptide sequences in insulin

Abstract

The synthesis is described of various derivatives of the peptides L-glutaminyl-S-benzyl-L-cysteine, L-glutaminyl-S-benzyl-L-cysteinyl-S-benzyl-L-cysteine, S-benzyl- L-cysteinyl-S-benzyl-L-cysteine, S-benzyl-L-cysteinyl-L-alanine, S-benzyl-L-cysteinyl-L-alanyl-L-serine, L-alanyl-L-serine, L-valyl-S-benzyl-L-cysteine, L-alanyl-L-seryl-L-valyl-S-benzyl-L-cysteine, S-benzyl-L-cysteinyl-L-alanyl-L-seryl-L-valyl-S-benzyl-L- cysteine, S-benzyl-L-cysteinylglycine, and L-leucyl-S-benzyl-L-cysteinylglycine.