The degradation of Trisnorlanostenolic Acid by the Curtius reaction

Abstract

As an alternative to the Barbier-Wieland degradation of trisnorlanostenolic acid (Curtis and Silberman 1952) degradation has been made through the Curtius reaction to the amine. This by quaternization and Hofmann deamination leads to the expected olefine which could serve as a starting point for further curtailment of the side chain.