Sulphonamides. IV. The Reaction of N-Heterocyclic Amines with Sulphonyl Halides

Abstract

The hypothesis is advanced that the reaction of sulphonyl halides with amino-derivatives of nitrogen-containing cyclic compounds occurs on the ring-nitrogen (which is the more basic), followed either by reaction of the amino-group with another molecule of sulphonyl halide, or by migration of the sulphonyl group from the ring to the ammo-nitrogen. Several apparently anomalous cases of this reaction are explained.