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RESEARCH ARTICLE
Contents Vol 67(9)

Annulation of Eight- to Ten-Membered Oxaza Rings to the Benzo[b]thiophene System by Intramolecular Nucleophilic Displacement

John B. Bremner A C and Zemin Wu A B
+ Author Affiliations
- Author Affiliations

A School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.

B Current address: Avipep Pty Ltd, 343 Royal Parade, Parkville, Vic. 3052, Australia.

C Corresponding author. Email: john_bremner@uow.edu.au

Australian Journal of Chemistry 67(9) 1217-1221 https://doi.org/10.1071/CH14055
Submitted: 5 February 2014  Accepted: 28 March 2014   Published: 22 April 2014

Abstract

Concise synthetic routes to 2H-benzo[b]thieno[3,2-b][1,5]oxazocin-6(3H)-one, and the new benzo[b]thieno[3,2-b][1,5]oxazonin-7(2H)-one and 2H-benzo[b]thieno[3,2-b][1,5]oxazecin-8(3H)-one systems, have been developed based on intramolecular nucleophilic displacement in the key ring forming step.


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