Total Synthesis of Bouchardatine
Nilesh H. Naik A B , Tukaram D. Urmode A , Arun K. Sikder B and Radhika S. Kusurkar A C
+ Author Affiliations
- Author Affiliations
A Department of Chemistry, University of Pune, Pune – 411 007, India.
B High Energy Materials Research Laboratory, Sutarwadi, Pune – 411 021, India.
C Corresponding author. Email: rsk@chem.unipune.ac.in
Australian Journal of Chemistry 66(9) 1112-1114 https://doi.org/10.1071/CH13331
Submitted: 27 June 2013 Accepted: 26 July 2013 Published: 26 August 2013
Abstract
Two new, efficient and simple routes using Heck-type reaction and intramolecular cyclization were developed for the synthesis of the naturally occurring cytotoxic alkaloid 2-(4-oxo-3,4-dihydroquinazolin-2-yl)-1H-indole-3-carbaldehyde (bouchardatine).
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