Synthesis of Poly(2-methyl-2-oxazoline) Star Polymers with a β-Cyclodextrin Core

Guillaume Pereira; Cécile Huin; Simona Morariu; Véronique Bennevault-Celton; Philippe Guégan

doi:10.1071/CH12232

RESEARCH FRONT

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Synthesis of Poly(2-methyl-2-oxazoline) Star Polymers with a β-Cyclodextrin Core

Guillaume Pereira ^A , Cécile Huin ^A , Simona Morariu ^B , Véronique Bennevault-Celton ^A ^C and Philippe Guégan ^A ^C

+ Author Affiliations

- Author Affiliations

^A LAMBE, UMR8587, University of Evry, 91025 Evry Cedex, France.

^B ‘Petru Poni’ Institute of Macromolecular Chemistry, 700487 Iasi, Romania.

^C Corresponding authors. Email: veronique.celton@univ-evry.fr; philippe.guegan@univ-evry.fr

Australian Journal of Chemistry 65(8) 1145-1155 https://doi.org/10.1071/CH12232
Submitted: 9 May 2012 Accepted: 22 June 2012 Published: 24 July 2012

Abstract

Synthesis of star polymers with a β-cyclodextrin (CD) core was undertaken using the arm-first, then the core-first strategy. Cationic ring opening polymerisation (CROP) of 2-methyl-2-oxazoline (MeOx) was first initiated by allyl bromide, and then quenched with heptakis(6-deoxy-6-amino)β-CD in order to get a 7-arm star polymer. Then heptakis(6-deoxy-6-iodo-2,3-di-O-acetyl)β-CD was synthesised in order to get an initiator for the CROP of MeOx. Initiation and propagation kinetic measurements were undertaken and the ratio k_p/k_i was found to be too high to provide a controlled polymerisation. Using iodine as co-initiator allowed a decrease of the k_p/k_i ratio that gave better control of the polymerisation. DOSY NMR and viscosity characterisations were undertaken, and both techniques lead to the demonstration of a lower hydrodynamic volume of the star polymers versus the linear counterparts, for compounds of the same molecular weight.

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Synthesis of Poly(2-methyl-2-oxazoline) Star Polymers with a β-Cyclodextrin Core

Abstract

References

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