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RESEARCH FRONT
Contents Vol 62(9)

Chiral Amine-Mediated Asymmetric Conjugate Additions to Vinyl Sulfones

Qiang Zhu A B and Yixin Lu A B C
+ Author Affiliations
- Author Affiliations

A Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.

B Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore, Singapore.

C Corresponding author. Email: chmlyx@nus.edu.sg

Australian Journal of Chemistry 62(9) 951-955 https://doi.org/10.1071/CH09137
Submitted: 10 March 2009  Accepted: 1 April 2009   Published: 17 September 2009

Abstract

Chiral molecules containing sulfone groups are useful intermediates and have found wide applications in organic synthesis. In this account, recent progress in the use of vinyl sulfones as Michael acceptors in the asymmetric organocatalytic conjugate addition is summarized.


Acknowledgements

The authors thank the National University of Singapore and the Ministry of Education of Singapore (R-143–000–362–112) for generous financial support.


References


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