Microfluidic Devices for Flow-Through Supported Palladium Catalysis on Porous Organic Monolith

Allan J. Canty; Jeremy A. Deverell; Anissa Gömann; Rosanne M. Guijt; Thomas Rodemann; Jason A. Smith

doi:10.1071/CH08160

RESEARCH ARTICLE

Microfluidic Devices for Flow-Through Supported Palladium Catalysis on Porous Organic Monolith

Allan J. Canty ^A , Jeremy A. Deverell ^A ^B , Anissa Gömann ^A ^B , Rosanne M. Guijt ^A ^B ^D , Thomas Rodemann ^C and Jason A. Smith ^A

+ Author Affiliations

- Author Affiliations

^A School of Chemistry, University of Tasmania, Private Bag 75, Hobart, TAS 7001, Australia.

^B Australian Centre for Research on Separation Science (ACROSS), School of Chemistry, University of Tasmania, Private Bag 75, Hobart, TAS 7001, Australia.

^C Central Science Laboratory (CSL), University of Tasmania, Private Bag 75, Hobart, TAS 7001, Australia.

^D Corresponding author. Email: rosanne.guijt@utas.edu.au

Australian Journal of Chemistry 61(8) 630-633 https://doi.org/10.1071/CH08160
Submitted: 17 April 2008 Accepted: 2 July 2008 Published: 15 August 2008

Abstract

Flow-through microreactors are described, constructed of fused silica capillaries with an internal diameter of 100 μm and glass microchips with a channel dimension of 150 μm and involving the in situ UV-initiated synthesis of a poly(glycidyl methacrylate-co-ethylene dimethacrylate) porous polymer monolith. The monolith is a continuous material covalently bonded to the capillary or chip walls, with good flow-through properties. Epoxide ring-opening through amine attack by 5-amino-1,10-phenanthroline and coordination to dichloropalladium(ii) allows use of the microreactors for Suzuki–Miyaura catalysis. The long-term stability and reliability of the robust chip microreactor is demonstrated by operation for 96 h, exhibiting undiminished reactivity, and very low leaching of palladium.

Acknowledgements

The present research was supported under the Australian Research Council’s Discovery Projects funding scheme (DP0663416) and the University of Tasmania Research College Board. Dr R. M. Guijt is the recipient of an ARC APD fellowship (DO0557803); Dr N. Davies, Mr P. Dove, Dr K. Gömann, and Dr A. Townsend (ICP-MS), Central Science Laboratory, are acknowledged for technical support; and Dr E. F. Hilder and Mrs K. F. Munting for useful discussions.

References

Microfluidic Devices for Flow-Through Supported Palladium Catalysis on Porous Organic Monolith

Abstract

Acknowledgements

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