Solution-Phase Peptide Synthesis; Synthesis of ‘North-Western’ and ‘South-Eastern’ Fragments of the Antifungal Cyclodepsipeptide Petriellin A

Luigi Aurelio; Robert T. C. Brownlee; Andrew B. Hughes

doi:10.1071/CH08132

RESEARCH ARTICLE

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Solution-Phase Peptide Synthesis; Synthesis of ‘North-Western’ and ‘South-Eastern’ Fragments of the Antifungal Cyclodepsipeptide Petriellin A

Luigi Aurelio ^A , Robert T. C. Brownlee ^B and Andrew B. Hughes ^B ^C

+ Author Affiliations

- Author Affiliations

^A Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, Parkville, Vic. 3052, Australia.

^B Department of Chemistry, La Trobe University, Melbourne, Vic. 3086, Australia.

^C Corresponding author. Email: a.hughes@latrobe.edu.au

Australian Journal of Chemistry 61(8) 615-629 https://doi.org/10.1071/CH08132
Submitted: 2 April 2008 Accepted: 2 July 2008 Published: 15 August 2008

Abstract

The solution-phase synthesis of two highly modified peptides, a hexamer and a heptamer, that constitute the two halves of the antifungal cyclic depsipeptide, Petriellin A, is reported.

Acknowledgement

L.A. acknowledges La Trobe University for the provision of a post-graduate scholarship.

References

Solution-Phase Peptide Synthesis; Synthesis of ‘North-Western’ and ‘South-Eastern’ Fragments of the Antifungal Cyclodepsipeptide Petriellin A

Abstract

Acknowledgement

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