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RESEARCH ARTICLE
Contents Vol 61(6)

Preparation and Surface Modification of Poly(acrylonitrile-co-acrylic acid) Electrospun Nanofibrous Membranes

Ai-Fu Che A , Xiao-Jun Huang A , Zhen-Gang Wang A and Zhi-Kang Xu A B
+ Author Affiliations
- Author Affiliations

A Institute of Polymer Science, Key Laboratory of Macromolecular Synthesis and Functionalization (Ministry of Education), Zhejiang University, Hangzhou 310027, China.

B Corresponding author. Email: xuzk@zju.edu.cn

Australian Journal of Chemistry 61(6) 446-454 https://doi.org/10.1071/CH07226
Submitted: 1 July 2007  Accepted: 14 April 2008   Published: 19 June 2008

Abstract

Poly(acrylonitrile-co-acrylic acid) (PANCAA) was synthesized and fabricated into nanofibrous membranes by an electrospinning technique. Scanning electron microscopy revealed that membranes composed of uniformly thin and smooth nanofibres were obtained under optimized processing parameters. Surface modification with chitosan on these nanofibrous membranes was accomplished by a coupling reaction between the carboxylic groups of PANCAA and the primary amino groups of chitosan. Fluorescent labelling, weight measurement, FT-IR/ATR spectroscopy, and X-ray photoelectron spectroscopy (XPS) were used to confirm the modification process and determine the immobilization degree of chitosan. Platelet adhesion experiments were further carried out to evaluate the hemocompatibility of the studied nanofibrous membranes. Preliminary results indicated that the immobilization of chitosan on the PANCAA nanofibrous membranes was favourable for platelet adhesion.


Acknowledgement

The authors are grateful for the financial support from the National Natural Science Foundation of China for Distinguished Young Scholars (to Prof. Z.-K. Xu, grant no. 50625309).


References


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