Anhydrous Magnesium Sulfate Mediated Solvent-Free Synthesis of Dihydropyrimidin-2(1H)-ones at Ambient Temperature
D. M. Pore A C , U. V. Desai A C , T. S. Thopate A and P. P. Wadgaonkar BA Department of Chemistry, Shivaji University, Kolhapur 416 004, India.
B Polymer Science and Engineering Division, National Chemical Laboratory, Pune 411008, India.
C Corresponding authors. Email: p_dattaprasad@rediffmail.com; uprabhu_desai@rediffmail.com
Australian Journal of Chemistry 60(6) 435-438 https://doi.org/10.1071/CH07097
Submitted: 6 April 2007 Accepted: 30 April 2007 Published: 18 June 2007
Abstract
An anhydrous magnesium sulfate mediated solvent-free protocol is described for the synthesis of dihydropyrimidinones (Biginelli compounds) at ambient temperature.
Acknowledgments
U.V.D. thanks UGC, New Delhi, for financial assistance (F.30-72/2004(SR)), and T.S.T. thanks UGC authorities for the award of a Teacher Fellowship under the faculty improvement program.
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