An Efficient and Green Procedure for the Preparation of 2-{2-[N′-(2-Hydroxybenzylidene)hydrazino]thiazol-4-yl}phenols

Vinod T. Kamble; Bhaskar S. Davane; Sanjay A. Chavan; Raghunath B. Bhosale

doi:10.1071/CH06377

RESEARCH ARTICLE

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An Efficient and Green Procedure for the Preparation of 2-{2-[N′-(2-Hydroxybenzylidene)hydrazino]thiazol-4-yl}phenols

Vinod T. Kamble ^A ^C , Bhaskar S. Davane ^B , Sanjay A. Chavan ^B and Raghunath B. Bhosale ^B

+ Author Affiliations

- Author Affiliations

^A Organic Chemistry Research Laboratory, School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431 606, M.S., India.

^B Research and Post Graduate Centre, Yeshwant College, Nanded-431 605, M.S., India.

^C Corresponding author. Email: vtkd@rediffmail.com

Australian Journal of Chemistry 60(4) 302-304 https://doi.org/10.1071/CH06377
Submitted: 16 October 2006 Accepted: 2 December 2006 Published: 26 April 2007

Abstract

An efficient and convenient approach for the synthesis of thiazole derivatives from α-halo ketones, thiosemicarbazide, and o-hydroxybenzaldehydes in poly(ethylene glycol) (PEG-400) is described. The preparation procedure presented is operationally simple and environmentally benign. Some of the major advantages of this procedure are high yields and ease of operation.

Acknowledgments

S.A.C. is thankful to the University Grants Commission for a fellowship under the Faculty Improvement Program (FIP). S.A.C. is also thankful to Dr A. S. Gawande, patron of Gopikabai Sitaram Gawande Science College, Umarkhed, M.S., India, for his support during this research work.

References

An Efficient and Green Procedure for the Preparation of 2-{2-[N′-(2-Hydroxybenzylidene)hydrazino]thiazol-4-yl}phenols

Abstract

Acknowledgments

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