The Genesis of the Reversible Radical Addition–Fragmentation–Transfer of Thiocarbonylthio Derivatives from the Barton–McCombie Deoxygenation: A Brief Account and Some Mechanistic Observations*

Samir Z. Zard

doi:10.1071/CH06263

RESEARCH FRONT

Previous Next Contents Vol 59(10)

The Genesis of the Reversible Radical Addition–Fragmentation–Transfer of Thiocarbonylthio Derivatives from the Barton–McCombie Deoxygenation: A Brief Account and Some Mechanistic Observations*

Samir Z. Zard ^A

+ Author Affiliations

- Author Affiliations

^A Laboratoire de Synthèse Organique associé au CNRS (UMR 7652), Département de Chimie, Ecole Polytechnique, 91128 Palaiseau, France. Email: zard@poly.polytechnique.fr

Samir Zard was born in 1955 in Ife, Nigeria. His chemical training started at the American University of Beirut, then Imperial College London, and finally Université Paris-Sud, where he received his Ph.D. supervised by Derek Barton. He commenced working with CNRS in 1981 but remained with Barton's group at Gif-sur-Yvette. He later moved to Palaiseau, where he explores new reactions and processes.

Australian Journal of Chemistry 59(10) 663-668 https://doi.org/10.1071/CH06263
Submitted: 25 July 2006 Accepted: 14 September 2006 Published: 30 October 2006

Abstract

The observations and reasoning leading to the discovery of the degenerative transfer of xanthates and related thiocarbonylthio derivatives are briefly described. A few synthetic applications are presented, and the consequences on the emergence of the RAFT and MADIX polymerization technologies as well as some mechanistic aspects are briefly discussed.

References

^* This paper is dedicated with respect and affection to the memory of Derek H. R. Barton.

The Genesis of the Reversible Radical Addition–Fragmentation–Transfer of Thiocarbonylthio Derivatives from the Barton–McCombie Deoxygenation: A Brief Account and Some Mechanistic Observations*

Abstract

Subscriber Login