Ionic Liquid Promoted Knoevenagel and Michael Reactions
Xuesen Fan A C , Xueyuan Hu A B , Xinying Zhang A and Jianji Wang AA School of Chemical and Environmental Sciences, Henan Key Laboratory for Environmental Pollution Control, Henan Normal University, Xinxiang, Henan 453007, China.
B Chongqing University of Medical Sciences, Chongqing 400016, China.
C Corresponding author. Email: fanxs88@263.net
Australian Journal of Chemistry 57(11) 1067-1071 https://doi.org/10.1071/CH04060
Submitted: 7 March 2004 Accepted: 9 July 2004 Published: 1 November 2004
Abstract
The utilization of the ionic liquid [bmim][BF4] as both reaction medium and promoter for the Knoevenagel condensation and Michael addition reactions is described in this paper. Through these reactions, several useful electrophilic alkenes and chromene derivatives are obtained in high yields. The advantages of these two novel procedures include their environmentally benign nature, atom economy, simple operation process, and mild reaction conditions.
Acknowledgment
This work was financially supported by the National Natural Science Foundation of China (no. 20273019).
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