Antifungal Thiosulfonates: Potency with Some Selectivity
Felix Jakob Baerlocher, Mark Otto Baerlocher, Crystal Lee Chaulk, Richard Francis Langler and Stephanie Lee MacQuarrie
Australian Journal of Chemistry
53(5) 399 - 402
Published: 2000
Abstract
A series of thiosulfonates have been prepared and tested against Aspergillus niger and Aspergillus flavus. In general, the thiosulfonates are moderate antifungal agents—more potent than corresponding inactive disulfides and less potent than corresponding very active fungitoxic disulfides. Apair of thiosulfonates show high selectivity, each killing only one kind of fungus.Keywords: Antifungal; fungitoxins; thiosulfonate synthesis; structure– activity.
https://doi.org/10.1071/CH00030
© CSIRO 2000
