Register      Login
Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Studies Towards the Synthesis of Phorbazoles A–D: Formation of the Pyrrole Oxazole Skeleton

Wendy A. Loughlin, I. Wayan Muderawan, Michelle A. McCleary, Katie E. Volter and Malcolm D. King

Australian Journal of Chemistry 52(3) 231 - 234
Published: 1999

Abstract

Synthetic approaches towards the synthesis of the pyrrole oxazole skeleton of phorbazoles A–D are described. An efficient synthesis of the pyrrole oxazole skeleton (19) from pyrrole and 4- methoxyacetophenone was developed. In the key step, cyclodehydration of the amide (16) resulted in formation of the diprotected pyrrole oxazole (17). Subsequent deprotection of the diprotected pyrrole oxazole (17) gave the target phorbazole skeleton (19).

https://doi.org/10.1071/C98169

© CSIRO 1999

Committee on Publication Ethics


Export Citation Get Permission

View Dimensions

View Altmetrics