cis-3-Hydroxy-N-methyl-L-proline: a New Amino Acid from a Southern Australian Marine Sponge, Dendrilla sp.

Abstract

A specimen of the sponge Dendrilla sp. collected during commercial trawling operations in the Great Australian Bight, Australia, analyses for a very high natural abundance of the new amino acid cis-3-hydroxy-N-methyl-L-proline (1). The complete stereostructure for (1) was determined by spectroscopic analysis and chemical derivatization.