Mutagenic Action of Phaseolinone, a Mycotoxin Isolated from Macrophomina phaseolina
Gautam Bhattacharya, Tarun K Dhar, F Kathleen Bhattacharya and Kazi A I Siddiqui
Australian Journal of Biological Sciences
40(4) 349 - 354
Published: 1987
Abstract
Phaseolinone was mutagenic to excision-repair-deficient strains of Escherichia coli WP2 and also to Salmonella typhimurium TA100. The repair test was indicative of covalent binding of the toxin to DNA. The side-chain epoxide and the hydroxy groups of the molecule were found to be essential for mutagenic activity.https://doi.org/10.1071/BI9870349
© CSIRO 1987
