Studies on Metatherian Sex Chromosomes VIII. Evidence for an Absence of Dosage Compensation at the Glucose-6-phosphate Dehydrogenase Locus in Cultured Cells of Macropus rufogriseus

Abstract

The level of the sex-linked enzyme glucose-6-phosphate dehydrogenase (G6PD) has been measured in cultured fibroblasts of M. rufogriseus and several other kangaroo species. The data obtained support the conclusion obtained from other evidence that there is a failure of dosage compensation at this locus in fibroblasts of females.