Control of Non-Allelic Recombination in Neurospora Crassa

Abstract

Two different recombination genes each control both allelic recombination and non-allelic recombination at a number of well-defined places in the genome of N. crassa. The dominant gene rec-3+ reduces allelic recombination at the am-l and his-2loci and in the segment between sn and his-2. The dominant gene rec-2+ reduces allelic recombination at the his-3 locus and in the three separate segments pyr-3 his-5, his-3 ad-3, and arg-3 sn. It is possible that rec-l+, which reduces allelic recombination at the his-l locus, also reduces non-allelic recombination between his-2 and his-3. The identity of rec-x with rec-3 is very highly probable; the identity of rec-w with rec-2 is also highly probable.