Effect of comorbidities on inpatient rehabilitation outcomes following non-traumatic lower limb amputations in Australia and New Zealand
Jack Peter Archer A * , Jacquelin Capell B , Judy Mullan C and Tara Alexander BA Wagga Wagga Base Hospital, 38 Spring Street, Wagga Wagga, NSW 2650, Australia.
B Australasian Rehabilitation Outcomes Centre (AROC), Australian Health Services Research Institute (AHSRI), University of Wollongong (UOW), Wollongong, NSW, Australia.
C Centre for Health Research Illawarra Shoalhaven Population (CHRISP), Australian Health Services Research Institute (AHSRI), University of Wollongong (UOW), Wollongong, NSW, Australia.
Australian Health Review 46(5) 613-620 https://doi.org/10.1071/AH21305
Submitted: 15 September 2021 Accepted: 23 February 2022 Published: 5 May 2022
© 2022 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of AHHA.
Abstract
Background Non-traumatic lower limb amputation rates are rising worldwide, resulting in increased hospitalisations and use of rehabilitation services. This study aimed to identify key comorbidities associated with prolonged length of stay or decreased functional gain for episodes receiving inpatient rehabilitation following non-traumatic lower limb amputation.
Methods Prospectively collected data submitted to the Australasian Rehabilitation Outcomes Centre were analysed. The cohort comprised episodes for patients (aged ≥18 years) discharged from inpatient rehabilitation between 1 July 2013 and 30 June 2018 following a non-traumatic lower limb amputation.
Results The cohort included 5074 episodes with an average age of 66.3 years and the majority being male (71.7%). Comorbidities affecting the ability to participate in rehabilitation were reported for 65.4% of episodes, most commonly diabetes mellitus (50.3%), cardiac disease (33.5%), and respiratory disease (10.1%). These comorbidities were associated with a prolonged length of stay and reduced functional improvement.
Conclusion This study showed comorbidities contribute to prolonged length of stay and poorer functional outcomes among those undergoing inpatient rehabilitation following non-traumatic lower limb amputation. Future research should focus on strategies to address these comorbidities to help improve patient outcomes and reduce healthcare costs.
Keywords: amputation, Australia, comorbidity, Functional Independence Measure, inpatients, length of stay, lower extremity, rehabilitation.
References
[1] Boulton A, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet 2005; 366 1719–1724.| The global burden of diabetic foot disease.Crossref | GoogleScholarGoogle Scholar | 16291066PubMed |
[2] Behrendt CA, Sigvant B, Szeberin Z, Beiles B, et al. International variations in amputation practice: a VASCUNET report. Eur J Vasc Endovasc Surg 2018; 56 391–399.
| International variations in amputation practice: a VASCUNET report.Crossref | GoogleScholarGoogle Scholar | 29859821PubMed |
[3] Australian Institute of Health and Welfare. Procedure data cubes 2013-2018. Canberra: AIHW; 2018. (cat. No. WEB216). Available at https://www.aihw.gov.au/reports/hospitals/procedures-data-cubes/contents/data-cubes
[4] Dillon M, Kohler F, Peeva V. Incidence of lower limb amputation in Australian hospitals from 2000 to 2010. Prosthet Orthot Int 2014; 38 122–132.
| Incidence of lower limb amputation in Australian hospitals from 2000 to 2010.Crossref | GoogleScholarGoogle Scholar | 23798042PubMed |
[5] Dillon MP, Fortington LV, Akram M, Erbas B, et al. Geographic variation of the incidence rate of lower limb amputation in Australia from 2007-12. PLoS One 2017; 12 e0170705
| Geographic variation of the incidence rate of lower limb amputation in Australia from 2007-12.Crossref | GoogleScholarGoogle Scholar | 28118408PubMed |
[6] Kurowski JR, Nedkoff L, Schoen DE, Knuiman M, et al. Temporal trends in initial and recurrent lower extremity amputations in people with and without diabetes in Western Australia from 2000 to 2010. Diabetes Res Clin Pract 2015; 108 280–287.
| Temporal trends in initial and recurrent lower extremity amputations in people with and without diabetes in Western Australia from 2000 to 2010.Crossref | GoogleScholarGoogle Scholar | 25765667PubMed |
[7] Kelly D, Pedersen S, Tosenovsky P, Sieunarine K. Major lower limb amputation: outcomes are improving. Ann Vasc Surg 2017; 1 29–34.
| Major lower limb amputation: outcomes are improving.Crossref | GoogleScholarGoogle Scholar |
[8] Venermo M, Manderbacka K, Ikonen T, Keskimäki I, Winell K, Sund R. Amputations and socioeconomic position among persons with diabetes mellitus, a population-based register study. BMJ Open 2013; 3 e002395
| Amputations and socioeconomic position among persons with diabetes mellitus, a population-based register study.Crossref | GoogleScholarGoogle Scholar | 23572197PubMed |
[9] Ulger O, Sahan T, Celik S. A systematic literature review of physiotherapy and rehabilitation approaches to lower-limb amputation. Physiother Theory Pract 2018; 34 821–834.
| A systematic literature review of physiotherapy and rehabilitation approaches to lower-limb amputation.Crossref | GoogleScholarGoogle Scholar | 29351504PubMed |
[10] Australasian Rehabilitation Outcomes Centre. AROC functional independence measure audit tool. Wollongong: AROC; 2021. Available at https://www.uow.edu.au/ahsri/aroc/fim-weefim/resources/ [updated 1 July 2021; cited 21 July 2021]
[11] Linacre JM, Heinemann AW, Wright BD, Granger CV, et al. The structure and stability of the functional independence measure. Phys Med Rehabil 1994; 75 127–132.
| The structure and stability of the functional independence measure.Crossref | GoogleScholarGoogle Scholar |
[12] Australasian Rehabilitation Outcomes Centre. AROC impairment codes – version 4 dataset. Wollongong: AROC; 2019. Available at https://documents.uow.edu.au/content/groups/public/@web/@chsd/@aroc/documents/doc/uow132298.pdf [updated 18 September 2019; cited 21 July 2021]
[13] Green J, Gordon R, Kobel C, Blanchard M, Eagar K. AN‐SNAP V4 User Manual, Centre for Health Service Development. University of Wollongong; 2015.
[14] Australasian Rehabilitation Outcomes Centre. Inpatient data dictionary version 4, for clinicians – Australian version. Wollongong: AROC; 2018. Available at https://apps.ahsri.uow.edu.au/confluence/display/AD/AROC+Data+Dictionaries [updated 05 June 2018; cited 21 July 2021]
[15] Australasian Rehabilitation Outcomes Centre. AROC Inpatient Data Collection Form – version 4 dataset. Wollongong: AROC; 2020. Available at https://apps.ahsri.uow.edu.au/confluence/display/AD/Data+Collection+Forms [updated 23 July 2020; cited 21 July 2021]
[16] De Laat FA, Dijkstra PU, Rommers GM, Geertzen JHB, et al. Prevalence of comorbidity and its association with demographic and clinical characteristics in persons wearing a prosthesis after a lower-limb amputation. J Rehabil Med 2018; 50 629–635.
| Prevalence of comorbidity and its association with demographic and clinical characteristics in persons wearing a prosthesis after a lower-limb amputation.Crossref | GoogleScholarGoogle Scholar | 29882579PubMed |
[17] Lazzarini P, Clark D, Derhy P. What are the major causes of lower limb amputations in a major Australian teaching hospital? The Queensland Diabetic Foot Innovation Project, 2006–2007. J Foot Ankle Res 2011; 4 O24
| What are the major causes of lower limb amputations in a major Australian teaching hospital? The Queensland Diabetic Foot Innovation Project, 2006–2007.Crossref | GoogleScholarGoogle Scholar |
[18] Baubeta Fridh E, Andersson M, Thuresson M, Sigvant B, et al. Amputation rates, mortality, and pre-operative comorbidities in patients revascularised for intermittent claudication or critical limb ischaemia: a population based study. Eur J Vasc Endovasc Surg 2017; 54 480–486.
| Amputation rates, mortality, and pre-operative comorbidities in patients revascularised for intermittent claudication or critical limb ischaemia: a population based study.Crossref | GoogleScholarGoogle Scholar | 28797662PubMed |
[19] Karmarker A, Graham J, Reistetter T, Ottenbacher K, et al. Association between functional severity and amputation type with rehabilitation outcomes in patients with lower limb amputation. Rehabil Res Prac 2014; 961798
| Association between functional severity and amputation type with rehabilitation outcomes in patients with lower limb amputation.Crossref | GoogleScholarGoogle Scholar |
[20] Robinson V, Sansam K, Hirst L, Neumann V. Major lower limb amputation – what, why and how to achieve the best results. Orthop Trauma 2010; 24 276–285.
| Major lower limb amputation – what, why and how to achieve the best results.Crossref | GoogleScholarGoogle Scholar |
[21] Pena G, Cowled P, Dawson J, Johnson B, et al. Diabetic foot and lower limb amputations: underestimated problem with a cost to health system and to the patient. ANZ J Surg 2018; 88 666–667.
| Diabetic foot and lower limb amputations: underestimated problem with a cost to health system and to the patient.Crossref | GoogleScholarGoogle Scholar |
[22] Independent Hospital Pricing Authority. National hospital cost data collection cost report: round 20 financial year 2015-16. Sydney: IHPA; 2018.