Free Standard AU & NZ Shipping For All Book Orders Over $80!
Register      Login
Australian Health Review Australian Health Review Society
Journal of the Australian Healthcare & Hospitals Association
RESEARCH ARTICLE

Identifying risk factors and patterns for unplanned readmission to a general medical service

Jordan Y. Z. Li B E G A , Tuck Y. Yong B E A , Paul Hakendorf C E , David I. Ben-Tovim C E and Campbell H. Thompson D F
+ Author Affiliations
- Author Affiliations

A Equal first authors.

B Department of General Medicine, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia. Email: tyyong@hotmail.com

C Clinical Epidemiology, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia. Email: paul.hakendorf@health.sa.gov.au; david.ben-tovim@flinders.edu.au

D Department of General Medicine, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia. Email: campbell.thompson@health.sa.gov.au

E School of Medicine, Flinders University, Medical Sciences Road, Bedford Park, SA 5042, Australia.

F School of Medicine, University of Adelaide, 30 Frome Road, Adelaide, SA 5000, Australia.

G Corresponding author. Email: jordan.li@health.sa.gov.au

Australian Health Review 39(1) 56-62 https://doi.org/10.1071/AH14025
Submitted: 3 February 2014  Accepted: 16 September 2014   Published: 13 November 2014

Abstract

Objective To identify factors and patterns associated with 7- and 28-day readmission for general medicine patients at a tertiary public hospital.

Methods A retrospective observational study was conducted using an administrative database at a general medicine service in a tertiary public hospital between 1 January 2007 and 31 December 2011. Demographic and clinical factors, as well as readmission patterns, were evaluated for the association with 7- and 28-day readmission.

Results The study cohort included 13 802 patients and the 28-day readmission rate was 10.9%. In multivariate analysis, longer hospital stay of the index admission (adjusted relative risk (ARR) 1.34), Charlson index ≥3 (ARR 1.28), discharge against medical advice (ARR 1.87), active malignancy (ARR 1.83), cardiac failure (ARR 1.48) and incomplete discharge summaries (ARR 1.61) were independently associated with increased risk of 28-day readmission. Patients with diseases of the respiratory system, neurological or genitourinary disease, injury and unclassifiable conditions were likely to be readmitted within 7 days. Patients with circulatory and respiratory disease were likely to be readmitted with the same system diagnosis.

Conclusion Readmission of general medicine patients within 28 days is relatively common and is associated with clinical factors and patterns. Identification of these risk factors and patterns will enable the interventions to reduce potentially preventable readmissions.

What is known about the topic? Readmission rates following hospitalization are increasing, especially among older patients and those with multiple underlying medical comorbidities. This presents a challenging and costly problem.

What does this paper add? Factors associated with increased risk of early readmission include higher comorbidity score, longer length of stay during the index admission and those who discharge against medical advice. Patients with respiratory, neurological or genitourinary disease, trauma and unclassifiable diagnosis were most at risk of early readmission. A large proportion of readmissions had principal diagnoses in a different diagnostic category to that of the index hospitalization.

What are the implications for practitioners? A breadth of system review is required before discharging any general medical patient. Intervention should be directed at a breadth of diagnoses and not just the principal diagnosis made during the index admission. Timing of implementation of the interventions is important and more urgent for some diagnoses than others.

Additional keywords: hospital discharge, rehospitalisation.


References

[1]  Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med 2009; 360 1418–28.
Rehospitalizations among patients in the Medicare fee-for-service program.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXjvFGju7c%3D&md5=751a313118dc84c28e77496baacaacfcCAS | 19339721PubMed |

[2]  Hasan O, Meltzer DO, Shaykevich SA, Bell CM, Kaboli PJ, Auerbach AD, Wetterneck TB, Arora VM, Zhang J, Schnipper JL. Hospital readmission in general medicine patients: a prediction model. J Gen Intern Med 2010; 25 211–9.
Hospital readmission in general medicine patients: a prediction model.Crossref | GoogleScholarGoogle Scholar | 20013068PubMed |

[3]  Brand C, Sundararajan V, Jones C, Hutchinson A, Campbell D. Readmission patterns in patients with chronic obstructive pulmonary disease, chronic heart failure and diabetes mellitus: an administrative dataset analysis. Intern Med J 2005; 35 296–9.
Readmission patterns in patients with chronic obstructive pulmonary disease, chronic heart failure and diabetes mellitus: an administrative dataset analysis.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2M3htFKhug%3D%3D&md5=65189dcac86c60a8066bcfd5eb44751fCAS | 15845113PubMed |

[4]  Centre for Medicare & Medicaid Services Hospital Inpatient Quality Reporting. 2013. Available at: http://www.qualitynet.org [verified 20 November 2013].

[5]  Leng GC, Walsh D, Fowkes FG, Swainson CP. Is the emergency readmission rate a valid outcome indicator? Qual Health Care 1999; 8 234–8.
Is the emergency readmission rate a valid outcome indicator?Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3M%2FgtlGjtw%3D%3D&md5=e4e34d0f14074ff20ae630ff756c56b3CAS | 10847885PubMed |

[6]  Jack BW, Chetty VK, Anthony D, Greenwald JL, Sanchez GM, Johnson AE, Forsythe SR, O’Donnell JK, Paasche-Orlow MK, Manasseh C, Martin S, Culpepper L. A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. Ann Intern Med 2009; 150 178–87.
A reengineered hospital discharge program to decrease rehospitalization: a randomized trial.Crossref | GoogleScholarGoogle Scholar | 19189907PubMed |

[7]  National Centre for Classification in Health. The International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Australian Modification (ICD-10-AM). Sydney: NCCH, University of Sydney, 1998.

[8]  Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC, Saunders LD, Beck CA, Feasby TE, Ghali WA. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 2005; 43 1130–9.
Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data.Crossref | GoogleScholarGoogle Scholar | 16224307PubMed |

[9]  Shu CC, Lin YF, Hsu NC, Ko WJ. Risk factors for 30-day readmission in general medical patients admitted from the emergency department: a single centre study. Intern Med J 2012; 42 677–82.
Risk factors for 30-day readmission in general medical patients admitted from the emergency department: a single centre study.Crossref | GoogleScholarGoogle Scholar | 21790921PubMed |

[10]  Mudge AM, Kasper K, Clair A, Redfern H, Bell JJ, Barras MA, Pachana NA. Recurrent readmissions in medical patients: a prospective study. J Hosp Med 2011; 6 61–7.
Recurrent readmissions in medical patients: a prospective study.Crossref | GoogleScholarGoogle Scholar | 20945294PubMed |

[11]  Hernandez AF, Curtis LH. Minding the gap between efforts to reduce readmissions and disparities. JAMA 2011; 305 715–6.
Minding the gap between efforts to reduce readmissions and disparities.Crossref | GoogleScholarGoogle Scholar | 21325191PubMed |

[12]  Coller RJ, Klitzner TS, Lerner CF, Chung PJ. Predictors of 30-day readmission and association with primary care follow-up plans. J Pediatr 2013; 163 1027–33.
Predictors of 30-day readmission and association with primary care follow-up plans.Crossref | GoogleScholarGoogle Scholar | 23706518PubMed |

[13]  Shorr AF, Zilberberg MD, Reichley R, Kan J, Hoban A, Hoffman J, Micek ST, Kollef MH. Readmission following hospitalization for pneumonia: the impact of pneumonia type and its implication for hospitals. Clin Infect Dis 2013; 57 362–7.
Readmission following hospitalization for pneumonia: the impact of pneumonia type and its implication for hospitals.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3sXhtFSiurrL&md5=6a285da28128179d1f4376bf94d0fc7cCAS | 23677872PubMed |

[14]  DeCoster V, Ehlman K, Conners C. Factors contributing to readmission of seniors into acute care hospitals. Educ Gerontol 2013; 39 878–87.
Factors contributing to readmission of seniors into acute care hospitals.Crossref | GoogleScholarGoogle Scholar |

[15]  Allaudeen N, Vidyarthi A, Maselli J, Auerbach A. Redefining readmission risk factors for general medicine patients. J Hosp Med 2011; 6 54–60.
Redefining readmission risk factors for general medicine patients.Crossref | GoogleScholarGoogle Scholar | 20945293PubMed |

[16]  Hoyer EH, Needham DM, Miller J, Deutschendorf A, Friedman M, Brotman DJ. Functional status impairment is associated with unplanned readmissions. Arch Phys Med Rehabil 2013; 94 1951–8.
Functional status impairment is associated with unplanned readmissions.Crossref | GoogleScholarGoogle Scholar | 23810355PubMed |

[17]  Graboyes EM, Liou TN, Kallogjeri D, Nussenbaum B, Diaz JA. Risk factors for unplanned hospital readmission in otolaryngology patients. Otolaryngol Head Neck Surg 2013; 149 562–71.
Risk factors for unplanned hospital readmission in otolaryngology patients.Crossref | GoogleScholarGoogle Scholar | 24042556PubMed |

[18]  van Walraven C, Dhalla IA, Bell C, Etchells E, Stiell IG, Zarnke K, Austin PC, Forster AJ. Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community. CMAJ 2010; 182 551–7.
Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community.Crossref | GoogleScholarGoogle Scholar | 20194559PubMed |

[19]  Li JY, Yong TY, Hakendorf P, Ben-Tovim D, Thompson CH. Timeliness in discharge summary dissemination is associated with patients’ clinical outcomes. J Eval Clin Pract 2013; 19 76–9.
Timeliness in discharge summary dissemination is associated with patients’ clinical outcomes.Crossref | GoogleScholarGoogle Scholar | 21999337PubMed |

[20]  Kripalani S, LeFevre F, Phillips CO, Williams MV, Basaviah P, Baker DW. Deficits in communication and information transfer between hospital-based and primary care physician. JAMA 2007; 297 831–41.
Deficits in communication and information transfer between hospital-based and primary care physician.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXisVSgsrs%3D&md5=4a5fd17c14dd8a3780f7f9782322589aCAS | 17327525PubMed |

[21]  Bell CM, Schnipper JL, Auerbach AD, Kaboli PJ, Weiterneck TB, Gonzales DV, Arora VM, Zhang JX, Meltzer DO. Association between communication between hospital-based physicians and primary care providers with patients outcomes. J Gen Intern Med 2009; 24 381–6.
Association between communication between hospital-based physicians and primary care providers with patients outcomes.Crossref | GoogleScholarGoogle Scholar | 19101774PubMed |

[22]  Choi M, Kim H, Qian H, Palepu A. Readmission rates of patients discharged against medical advice: a matched cohort study. PLoS ONE 2011; 6 e24459
Readmission rates of patients discharged against medical advice: a matched cohort study.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXht1ChsbrN&md5=189e04b067e5c28e78bdbd5f67374dbcCAS | 21931723PubMed |

[23]  Yong TY, Fok JS, Hakendorf P, Ben-Tovim D, Thompson CH, Li JY. Characteristics and outcomes of discharges against medical advice among hospitalized patients. Intern Med J 2013; 43 798–802.
Characteristics and outcomes of discharges against medical advice among hospitalized patients.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3svjtlOnsQ%3D%3D&md5=a5c585d6f230cad1b8b28e7e5c6616eaCAS | 23461391PubMed |

[24]  Krumholz HM. Post-hospital syndrome: an acquired, transient condition of generalized risk. N Engl J Med 2013; 368 100–2.
Post-hospital syndrome: an acquired, transient condition of generalized risk.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3sXovVyitg%3D%3D&md5=5f8e302b020dbdb18a86708d0d0a4b12CAS | 23301730PubMed |

[25]  Howell S, Coory M, Martin J, Duckett S. Using routine inpatient data to identify patients at risk of hospital readmission. BMC Health Serv Res 2009; 9 96
Using routine inpatient data to identify patients at risk of hospital readmission.Crossref | GoogleScholarGoogle Scholar | 19505342PubMed |

[26]  Garcia-Perez L, Linertova R, Lorenzo-Riera A, Vazquez-Diaz JR, Duque-Gonzalez B, Sarria-Santamera A. Risk factors for hospital readmissions in elderly patients: a systematic review. QJM 2011; 104 639–51.
Risk factors for hospital readmissions in elderly patients: a systematic review.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3MnovFGrsA%3D%3D&md5=283f48c55a4d1d4b7598df959eb455a4CAS | 21558329PubMed |

[27]  Franchi C, Nobili A, Mari D, Tettamanti M, Djade CD, Pasina L, Salernoc F, Corraod S, Marengonie A, Ioriof A, Marcuccif M, Mannuccio Mannucci P. Risk factors for hospital readmissions of elderly patients. Eur J Intern Med 2013; 24 45–51.
Risk factors for hospital readmissions of elderly patients.Crossref | GoogleScholarGoogle Scholar | 23142413PubMed |

[28]  Scott IA, Shohag H, Ahmed M. Quality of care factors associated with unplanned readmissions of older medical patients: a case-control study. Intern Med J 2014; 44 161–70.
Quality of care factors associated with unplanned readmissions of older medical patients: a case-control study.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC2c3kslGnsA%3D%3D&md5=1f95caf31b48ebde2bbc509da18e750bCAS | 24320739PubMed |

[29]  Scott IA. Preventing the rebound: improving care transition in hospital discharge processes. Aust Health Rev 2010; 34 445–51.
Preventing the rebound: improving care transition in hospital discharge processes.Crossref | GoogleScholarGoogle Scholar | 21108906PubMed |

[30]  McCarthy D. Recasting readmissions by placing the hospital role in community context. JAMA 2013; 309 351–2.
Recasting readmissions by placing the hospital role in community context.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3sXhsFGgs70%3D&md5=8bb27a21f56fe724d7e9b3be69af4e80CAS | 23340635PubMed |

[31]  Ryan J, Andrews R, Barry MB, Kang S, Iskander A, Mehla P, Ganeshan R. Preventability of 30-day readmissions for heart failure patients before and after a quality improvement initiative. Am J Med Qual 2014; 29 220–6.
Preventability of 30-day readmissions for heart failure patients before and after a quality improvement initiative.Crossref | GoogleScholarGoogle Scholar | 23956341PubMed |

[32]  Hersh AM, Masoudi FA, Allen LA. Postdischarge environment following heart failure hospitalization: expanding the view of hospital readmission. J Am Heart Assoc 2013; 2 e000116
Postdischarge environment following heart failure hospitalization: expanding the view of hospital readmission.Crossref | GoogleScholarGoogle Scholar | 23580604PubMed |