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Australian Health Review Australian Health Review Society
Journal of the Australian Healthcare & Hospitals Association
RESEARCH ARTICLE

In-hospital cardiac arrests: effect of amended Australian Resuscitation Council 2006 guidelines

Mary S. Boyde A C , Michelle Padget A , Elizabeth Burmeister A B and Leanne M. Aitken A B
+ Author Affiliations
- Author Affiliations

A Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Qld 4102, Australia. Email: michelle_padget@health.qld.gov.au; liz_burmeister@health.qld.gov.au

B Centre for Health Practice Innovation, Griffith Health Institute, Griffith University, 170 Kessels Road, Nathan, Qld 4111, Australia. Email: l.aitken@griffith.edu.au

C Corresponding author. Email: mary_boyde@health.qld.gov.au

Australian Health Review 37(2) 178-184 https://doi.org/10.1071/AH11112
Submitted: 13 November 2011  Accepted: 11 November 2012   Published: 9 April 2013

Abstract

Objective To evaluate cardiac arrest outcomes following the introduction of the Australian Resuscitation Council (ARC) 2006 amended guidelines for basic and advanced life support.

Methods A retrospective study of all consecutive cardiac arrests during a 3-year phase pre-implementation (2004–06) and a 3-year phase post-implementation (2007–09) of the ARC 2006 guidelines was conducted at a tertiary referral hospital in Brisbane, Australia.

Results Over the 6-year study phase 690 cardiac arrests were reported. Resuscitation was attempted in 248 patients pre-implementation and 271 patients post-implementation of the ARC 2006 guidelines. After adjusting for significant prognostic factors we found no significant change in return of spontaneous circulation (ROSC) (odds ratio 1.21, 95% confidence interval 0.80–1.85, P = 0.37) or survival to discharge (odds ratio 1.49, 95% confidence interval 0.94–2.37, P = 0.09) after the implementation of the ARC 2006 guidelines. Factors that remained significant in the final model for both outcomes included having an initial shockable rhythm, a shorter length of time from collapse to arrival of cardiac arrest team, location of the patient in a critical-care area, shorter length of resuscitation and a day-time arrest (0700–2259 hours). In addition the arrest being witnessed was significant for ROSC and younger age was significant for survival to discharge.

Conclusions There are multiple factors that influence clinical outcomes following an in-hospital cardiac arrest and further research to refine these significant variables will assist in the future management of cardiac arrests.

What is known about this topic? The evaluation of outcomes from in-hospital cardiac arrests focuses on immediate survival expressed as ROSC and survival to hospital discharge. These clinical outcomes have not improved substantially over the last two decades.

What does this paper add? This paper identifies the factors that are related to ROSC and survival to discharge following the implementation of the ARC 2006 guidelines, which included a refocus on providing quality cardiopulmonary resuscitation with minimal interruptions.

What are the implications for practitioners? Given that multiple factors can influence clinical outcomes following an in-hospital cardiac arrest, focusing on maximising a range of factors surrounding cardiopulmonary resuscitation is essential to improve outcomes.


References

[1]  Chan P, Nichol G, Krumholz H, Spertus J, Nallamothu B. Hospital variation in time to defibrillation after in-hospital cardiac arrest. Arch Intern Med 2009; 169 1265–73.
Hospital variation in time to defibrillation after in-hospital cardiac arrest.Crossref | GoogleScholarGoogle Scholar | 19636027PubMed |

[2]  Ehlenbach W, Barnato A, Curtis J, Kreuter W, Koepsell T, Deyo R, et al Epidemiologic study of in-hospital cardiopulmonary resuscitation in the elderly. N Engl J Med 2009; 361 22–31.
Epidemiologic study of in-hospital cardiopulmonary resuscitation in the elderly.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXotVOqtb0%3D&md5=c8de76a181670b70c32195d91d39d587CAS | 19571280PubMed |

[3]  International Liaison Committee on Resuscitation Part 2: adult basic life support. Resuscitation 2005; 67 187–201.
Part 2: adult basic life support.Crossref | GoogleScholarGoogle Scholar | 16324988PubMed |

[4]  Australian Resuscitation Council (ARC). ARC Guidelines. Melbourne: ARC; 2006.

[5]  Abella B, Sandbo N, Vassilatos P, Alvarado J, O’Hearn N, Wigder H, et al Chest compression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest. Circulation 2005; 111 428–34.
Chest compression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest.Crossref | GoogleScholarGoogle Scholar | 15687130PubMed |

[6]  Losert A, Kohler K, Sodeck G, Fleischhackl R, Eisenburger P, Kliegel A, et al Quality of cardiopulmonary resuscitation among highly trained staff in emergency department setting. Arch Intern Med 2006; 166 2375–80.
Quality of cardiopulmonary resuscitation among highly trained staff in emergency department setting.Crossref | GoogleScholarGoogle Scholar |

[7]  Australian Resuscitation Council (ARC). Cardiopulmonary Resuscitation and Guideline 11: Adult Advanced Life Support. Melbourne: ARC; 2006.

[8]  Morley P, Walker T. Australian Resuscitation Council. Critical Care and Resuscitation 2006; 8 129–31.
| 16749880PubMed |

[9]  Jacobs I, Nadkarni V, Bahr J, Berg R, Billi J, Bossaert L, et al Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation. Resuscitation 2004; 63 233–49.
Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation.Crossref | GoogleScholarGoogle Scholar | 15582757PubMed |

[10]  Peters R, Boyde M. Improving survival after in-hospital cardiac arrest: the Australian experience. Am J Crit Care 2007; 16 240–6.
| 17460315PubMed |

[11]  Thigpen K, Davis S, Basol R, Lange P, Jain S, Olsen J, et al Implementing the 2005 American Heart Association Guidelines, including use of the Impedance Threshold Device, improves hospital discharge rate after in-hospital cardiac arrest. Respir Care 2010; 55 1014–9.
| 20667148PubMed |

[12]  Hazinski M, Nadkarni V, Hickey R, O’Connor R, Becker L, Zaritsky A. Major changes in the 2005 AHA Guidelines for CPR and ECC: reaching the tipping point for change. Circulation 2005; 112 IV-206–11.
Major changes in the 2005 AHA Guidelines for CPR and ECC: reaching the tipping point for change.Crossref | GoogleScholarGoogle Scholar |

[13]  Bakhtiar A, Zafari M. Narrative review: cardioplumonary resuscitation and emergency cardiovascular care: review of the current guidelines. Ann Intern Med 2007; 147 171–9.

[14]  Klocko D. Have the latest CPR guidelines improved cardiac arrest outcomes? JAAPA 2009; 22 30–9.
| 19999174PubMed |

[15]  Rea T, Helbock M, Perry S, Garcia M, Cloyd D, Becker L, et al Increasing use of cardiopulmonary resuscitation during out-of-hospital ventricullar arrest: survival implications of guideline changes. Circulation 2006; 114 2760–5.
Increasing use of cardiopulmonary resuscitation during out-of-hospital ventricullar arrest: survival implications of guideline changes.Crossref | GoogleScholarGoogle Scholar | 17159062PubMed |

[16]  Olasveengen M, Vik E, Kuzovlev A, Sunde K. Effect of implementation of new resuscitation guidelines on quality of cardiopulmonary resuscitation and survival. Resuscitation 2009; 80 407–11.
Effect of implementation of new resuscitation guidelines on quality of cardiopulmonary resuscitation and survival.Crossref | GoogleScholarGoogle Scholar |

[17]  Nadkarni V, Larkin G, Peberdy M, Carey S, Kaye W, Mancini M, et al First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults. JAMA 2006; 295 50–7.
First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XhtlKgsw%3D%3D&md5=b7b9be13708e12cbb3a813576d9b5f65CAS | 16391216PubMed |

[18]  Sandroni C, Nolan J, Cavallaro F, Antonelli M. In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival. Intensive Care Med 2007; 33 237–45.
In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival.Crossref | GoogleScholarGoogle Scholar | 17019558PubMed |

[19]  Meaney P, Nadkarni V, Kern K, Indik J, Halperin H, Berg R. Rhythms and outcomes of adult in-hospital cardiac arest. Crit Care Med 2010; 38 101–8.
Rhythms and outcomes of adult in-hospital cardiac arest.Crossref | GoogleScholarGoogle Scholar | 19770741PubMed |

[20]  Cooper S, Janghorbani M, Cooper G. A decade of in-hospital resuscitation: Outcomes and prediction of survival? Resuscitation 2006; 68 231–7.
A decade of in-hospital resuscitation: Outcomes and prediction of survival?Crossref | GoogleScholarGoogle Scholar | 16325314PubMed |

[21]  Peberdy M, Kaye W, Ornato J, Larkin G, Nadkarni V, Mancini M, et al Cardiopulmonary resuscitation of adults in the hospital: a report of 14 720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation. Resuscitation 2003; 58 297–308.
Cardiopulmonary resuscitation of adults in the hospital: a report of 14 720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation.Crossref | GoogleScholarGoogle Scholar | 12969608PubMed |

[22]  Shih C, Lu T, Jerng J, Lin C, Liu Y, Chen W, et al A web-based Utstein style registry system of in-hospital cardiopulmonary resuscitation in Taiwan. Resuscitation 2007; 72 394–403.
A web-based Utstein style registry system of in-hospital cardiopulmonary resuscitation in Taiwan.Crossref | GoogleScholarGoogle Scholar | 17161519PubMed |

[23]  Herlitz J, Bang A, Anune S, Ekstrom L, Lundstrom G, Holmberg S. Characteristics and outcome among patients suffering in-hospital cardiac arrests in monitored and nonmonitored areas. Resuscitation 2001; 48 125–35.
Characteristics and outcome among patients suffering in-hospital cardiac arrests in monitored and nonmonitored areas.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3MzmsFGnsg%3D%3D&md5=a5d65427ff66bf92b72562dfe63840d7CAS | 11426474PubMed |

[24]  Peberdy M, Ornato J, Larkin G, Braithwaite R, Kashner T, Carey S, et al Survival from in-hospital cardiac arrest during nights and weekends. JAMA 2008; 299 785–92.
Survival from in-hospital cardiac arrest during nights and weekends.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXitlGjs70%3D&md5=1ae869c464ada2cbbcdf65bfb0a55fd3CAS | 18285590PubMed |

[25]  Hinchey P, Brent Myers J, Lewis R, De Maio V, Reyer E, Licatese D, et al Improved out-of-hospital cardiac arrest survival after the sequential implementation of the 2005 AHA Guidelines for compression, ventilations, and induced hypothermia: The Wake County Experience. Ann Emerg Med 2010; 56 348–57.
Improved out-of-hospital cardiac arrest survival after the sequential implementation of the 2005 AHA Guidelines for compression, ventilations, and induced hypothermia: The Wake County Experience.Crossref | GoogleScholarGoogle Scholar | 20359771PubMed |

[26]  Australian Resuscitation Council (ARC). ARC Guidelines. Melbourne: ARC; 2010.