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REVIEW
Contents Vol 67(6)

Fungal Metabolites as Pharmaceuticals

Andrew M. Beekman A and Russell A. Barrow A B
+ Author Affiliations
- Author Affiliations

A Research School of Chemistry, Australian National University, Canberra, ACT 0200, Australia.

B Corresponding author. Email: rab@anu.edu.au




Andrew Beekman is currently a postdoctoral researcher at the Australian National University. Andrew studied for his B.Sc.(Adv.) at the Australian National University and received an Honours degree in 2009. He began his Ph.D. studies in 2010 with Dr Russell Barrow at the Research School of Chemistry as an Alan Sargeson Scholar, focusing on the elucidation and synthesis of biologically significant fungal metabolites from traditional medicinal sources, completing his thesis in 2013. In 2014, he will begin an Endeavour Postdoctoral Research Fellowship at the University of British Columbia


Russell Barrow is a group leader (Organic Chemistry of Natural Systems) at the Research School of Chemistry, Australian National University. After completing B.Sc.(Hons.) and Ph.D. degrees at Melbourne University, he undertook postdoctoral research at The University of Hawaii, focusing on the isolation and synthesis of natural products. Current research interests include studying the chemistry supporting the traditional use of fungi in Papua New Guinea, where he has an adjunct appointment at the University of Goroka.

Australian Journal of Chemistry 67(6) 827-843 https://doi.org/10.1071/CH13639
Submitted: 19 November 2013  Accepted: 4 March 2014   Published: 19 May 2014

Abstract

Natural products, their derivatives or compounds based on natural product leads constitute ~50 % of clinically used pharmaceuticals. This review highlights pharmaceuticals currently used in Australia and New Zealand that have their origins in fungal metabolites, discussing the natural products chemistry and medicinal chemistry leading to their application as pharmaceuticals.


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