CH25059The development of a bioassay expressing the human MRGPRX2 receptor for ex vivo drug discovery
Mast cells of our immune system are generally difficult and expensive to maintain in vitro and, therefore, not economical to use in drug discovery. The development of a bioassay expressing the human mas-related G protein-coupled receptor-X2 receptor linked to potassium channels in a host cell offers a good alternative. (Image credit: Jan Tytgat.)
This article belongs to the collection: 70th Birthday tribute to Professor David Craik.
CH25059 Abstract | CH25059 Full Text | CH25059PDF (1.2 MB) Open Access Article