Australian Journal of Chemistry 66 (12) pp.1463
- 1464
Fragment-Based Drug Discovery
A two-day workshop ‘Fragment-Based Drug Design Down Under’ was held at the Monash Institute of Pharmaceutical Sciences, Parkville, in November 2012. This Research Front captures the spirit of this workshop and highlights some of the leading work undertaken in Australia in this rapidly developing area.
Published 07 October 2013
Design and Evaluation of the Performance of an NMR Screening Fragment Library
Bradley C. Doak , Craig J. Morton , Jamie S. Simpson , Martin J. Scanlon
Australian Journal of Chemistry 66 (12) pp.1465
- 1472
Published 17 October 2013
Construction of the CSIRO Fragment Library
Craig L. Francis , Peter W. Kenny , Olan Dolezal , Simon Saubern , Megan Kruger , G. Paul Savage , Thomas S. Peat , John H. Ryan
Australian Journal of Chemistry 66 (12) pp.1473
- 1482
Published 02 December 2013
PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening
Jonathan B. Baell , Lori Ferrins , Hendrik Falk , George Nikolakopoulos
Australian Journal of Chemistry 66 (12) pp.1483
- 1494
Australian Journal of Chemistry 66 (12) pp.1495
- 1501
Published 05 September 2013
Interrogating Fragments Using a Protein Thermal Shift Assay
Róisín M. McMahon , Martin J. Scanlon , Jennifer L. Martin
Australian Journal of Chemistry 66 (12) pp.1502
- 1506
Published 01 August 2013
Fragment Screening for the Modelling Community: SPR, ITC, and Crystallography
Olan Dolezal , Larissa Doughty , Meghan K. Hattarki , Vincent J. Fazio , Tom T. Caradoc-Davies , Janet Newman , Thomas S. Peat
Australian Journal of Chemistry 66 (12) pp.1507
- 1517
Published 02 September 2013
Detection and Prevention of Aggregation-based False Positives in STD-NMR-based Fragment Screening
Amelia Vom , Stephen Headey , Geqing Wang , Ben Capuano , Elizabeth Yuriev , Martin J. Scanlon , Jamie S. Simpson
Australian Journal of Chemistry 66 (12) pp.1518
- 1524
Published 16 September 2013
Blind Man’s Bluff – Elaboration of Fragment Hits in the Absence of Structure for the Development of Antitrypsin Deficiency Inhibitors
Stephen J. Headey , Mary C. Pearce , Martin J. Scanlon , Stephen P. Bottomley
Australian Journal of Chemistry 66 (12) pp.1525
- 1529
Published 26 August 2013
Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening
San Sui Lim , Cael O. Debono , Christopher A. MacRaild , Indu R. Chandrashekaran , Olan Dolezal , Robin F. Anders , Jamie S. Simpson , Martin J. Scanlon , Shane M. Devine , Peter J. Scammells , Raymond S. Norton
Australian Journal of Chemistry 66 (12) pp.1530
- 1536
Published 20 September 2013
Fragment Screening on Staphylococcus aureus HPPK – a Folate Pathway Target
Sandeep Chhabra , Olan Dolezal , Meghan Hattarki , Thomas S. Peat , Jamie S. Simpson , James D. Swarbrick
Australian Journal of Chemistry 66 (12) pp.1537
- 1543
Published 05 August 2013
Fragment-based Drug Discovery: the Shape of Things to Come
Martin J. Drysdale
Australian Journal of Chemistry 66 (12) pp.1544
- 1549