The Acute Toxicity of Cholecalciferol to the European Rabbit, Oryctolagus Cuniculus.

Abstract

The toxicity of cholecalciferol in the rabbit was evaluated as part of an assessment of alternative toxins to sodium monofluoroacetate (1080) and pindone for large-scale rabbit control in the South Island of New Zealand. After a dose-ranging study spanning the known LD50 values for other mammals (up to 400 mg kg-1) an acute toxicity study established an LD50 of 9mg kg-1 and LD95 of 18mg kg-1 for the rabbit, which proved very susceptible to cholecalciferol.