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RESEARCH ARTICLE
Contents Vol 4(1)

Human adenoviruses types associated with non-gonococcal urethritis

Sepehr N. Tabrizi A C E , Alison E. Ling A , Catriona S. Bradshaw B D , Christopher K. Fairley B D and Suzanne M. Garland A C
+ Author Affiliations
- Author Affiliations

A Department of Microbiology and Infectious Diseases, The Royal Women’s Hospital, Carlton 3053, Victoria, Australia.

B Melbourne Sexual Health Centre, 580 Swanston St, Carlton 3053, Victoria, Australia.

C Department of Obstetrics and Gynaecology, University of Melbourne, Parkville 3052, Victoria, Australia.

D School of Population Health, University of Melbourne, Parkville 3052, Victoria, Australia.

E Corresponding author. Email: sepehr.tabrizi@rch.org.au

Sexual Health 4(1) 41-44 https://doi.org/10.1071/SH06054
Submitted: 23 September 2006  Accepted: 25 January 2007   Published: 26 February 2007

Abstract

Background: Role of adenoviruses in non-gonococcal urethritis (NGU) has been reported in only a few studies. The aim of the study was to detect and type adenoviruses in men presenting with NGU. Methods: 636 heterosexual and homosexual men presenting with NGU from Melbourne, Australia were recently evaluated for various aetiological organisms including adenovirus. We utilised methods including polymerase chain reaction for detection followed by sequence analysis to type positive samples. Results: Overall, 12 samples from patients with NGU had adenovirus detected. Five types were identified: type 4 (subgenus E), type 35 (subgenus B), and types 9, 37 and 49 (subgenus D). The presence of mixed adenovirus strains was not detected in any sample. Conclusion: Overall, subgenus B, D and E were predominant in this patient population.

Additional keywords: real-time PCR, sequence-based typing.


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