A New Preparation of the Diastereoisomeric N -Acetylneuraminic Alditols
Hua Chee Ooi, Sebastian M. Marcuccio and W. Roy Jackson
Australian Journal of Chemistry
53(3) 171 - 174
Published: 2000
Abstract
Acylation of the alditols (2) obtained by sodium borohydride reduction of N-acetylneuraminic acid (Neu5Ac) (1) gives a mixture of lactones (3) and (4) which can be separated and deprotected without epimerization yielding pure samples of the diastereoisomeric N-acetylneuraminic alditols (5) and (6).Keywords: Acetylneuraminic alditols; diastereoisomers; separation.
https://doi.org/10.1071/CH99140
© CSIRO 2000
