Reactions in frozen aqueous solutions : The kinetics of the reaction of morpholine with Dihydrothiophen-2(3H)-one and with methyl formate

Abstract

The reactions of morpholine with dihydrothiophen-2(3H)-one and with methyl formate have been studied in frozen solution at -10°C. The rates for these reactions are the same as those found when reaction is carried out at the same temperature in simple solutions with concentrations equal to those present in the equilibrium liquid phase of the partly frozen solution. These observations show that the change in rate is a pure concentration effect. There is no need to assume any change in order or mechanism of reaction in the frozen solution as was claimed by Bruice and Butler.